David Capper Selected Research

Messenger RNA (mRNA)

9/2015	Molecular profiling of long-term survivors identifies a subgroup of glioblastoma characterized by chromosome 19/20 co-gain.
12/2014	MAP kinase activity supported by BRAF (V600E) mutation rather than gene amplification is associated with ETV1 expression in melanoma brain metastases.
10/2014	Primary glioblastoma cultures: can profiling of stem cell markers predict radiotherapy sensitivity?
10/2013	Differential expression of the tumor suppressor A-kinase anchor protein 12 in human diffuse and pilocytic astrocytomas is regulated by promoter methylation.
9/2010	Defective p53 antiangiogenic signaling in glioblastoma.

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David Capper Research Topics

Disease

103	Neoplasms (Cancer) 05/2024 - 02/2006
45	Glioma (Gliomas) 05/2024 - 05/2007
35	Glioblastoma (Glioblastoma Multiforme) 05/2024 - 02/2008
30	Astrocytoma (Pilocytic Astrocytoma) 01/2023 - 02/2008
14	Brain Neoplasms (Brain Tumor) 02/2024 - 03/2011
12	Melanoma (Melanoma, Malignant) 01/2022 - 02/2012
10	Oligodendroglioma 01/2017 - 10/2009
9	Sarcoma (Soft Tissue Sarcoma) 11/2022 - 06/2011
5	Neoplasm Metastasis (Metastasis) 02/2024 - 02/2012
5	Ganglioglioma 12/2022 - 06/2013
4	Medulloblastoma 05/2023 - 01/2016
4	Neuroepithelial Neoplasms (Gliomatosis Cerebri) 10/2019 - 01/2014
3	Hypoxia (Hypoxemia) 09/2022 - 03/2013
3	Adenoma (Adenomas) 01/2020 - 02/2006
3	Primitive Neuroectodermal Tumors (PNET) 10/2018 - 01/2016
3	Cholangiocarcinoma 01/2017 - 07/2014
3	Carcinoma (Carcinomatosis) 03/2013 - 06/2011
2	B-Cell Lymphoma (Lymphoma, B Cell) 11/2023 - 05/2020
2	Disease Progression 10/2023 - 05/2021
2	Ependymoma 01/2023 - 01/2019
2	Squamous Cell Neoplasms (Squamous Cell Cancer) 01/2022 - 10/2013
2	Lymphoma (Lymphomas) 05/2020 - 07/2013
2	Choroid Plexus Neoplasms (Choroid Plexus Tumor) 01/2019 - 03/2016
2	Carcinogenesis 01/2019 - 07/2014
2	Necrosis 11/2018 - 04/2009
2	Pituitary Neoplasms (Pituitary Adenoma) 01/2018 - 02/2006
2	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 01/2017 - 08/2010
2	Chondrosarcoma 01/2017 - 04/2014
2	Liver Neoplasms (Liver Cancer) 06/2016 - 07/2014
2	Neurilemmoma (Schwannoma) 01/2016 - 04/2014
2	Neurofibrosarcoma (MPNST) 01/2016 - 04/2014
2	Central Nervous System Cysts (Suprasellar Cyst) 10/2015 - 04/2008
2	Liposarcoma 11/2014 - 04/2014
2	Adenocarcinoma 07/2014 - 10/2013
2	Papillary Thyroid Cancer 05/2014 - 06/2012
2	Solitary Fibrous Tumors 04/2014 - 05/2013
2	Colorectal Neoplasms (Colorectal Cancer) 10/2013 - 02/2012
2	Ovarian Neoplasms (Ovarian Cancer) 09/2013 - 02/2012
2	Meningioma (Meningiomas) 05/2013 - 03/2013

Drug/Important Bio-Agent (IBA)

34	Proteins (Proteins, Gene)FDA Link 12/2022 - 07/2005
23	Isocitrate Dehydrogenase (Isocitrate Dehydrogenase (NAD+))IBA 12/2022 - 10/2009
20	DNA (Deoxyribonucleic Acid)IBA 05/2024 - 03/2010
14	Biomarkers (Surrogate Marker)IBA 02/2024 - 07/2011
11	Phosphotransferases (Kinase)IBA 01/2023 - 03/2013
9	ParaffinIBA 05/2015 - 11/2009
7	RNA (Ribonucleic Acid)IBA 11/2023 - 01/2019
7	Formaldehyde (Formol)FDA Link 05/2015 - 11/2009
6	Histones (Histone)IBA 12/2023 - 08/2013
6	Temozolomide (Temodar)FDA LinkGeneric 10/2020 - 07/2015
6	Monoclonal AntibodiesIBA 10/2015 - 01/2010
5	Codon (Codons)IBA 01/2017 - 01/2010
5	Messenger RNA (mRNA)IBA 09/2015 - 09/2010
4	Mitogen-Activated Protein KinasesIBA 01/2024 - 03/2013
4	Transcription Factors (Transcription Factor)IBA 01/2019 - 04/2014
3	Growth Factor ReceptorsIBA 01/2023 - 02/2012
3	LY-2157299IBA 10/2020 - 01/2016
3	AntigensIBA 01/2019 - 02/2015
3	Transforming Growth Factors (Transforming Growth Factor)IBA 05/2017 - 08/2009
3	alpha-hydroxyglutarateIBA 01/2017 - 01/2012
3	NestinIBA 06/2016 - 07/2014
3	Mutant Proteins (Protein, Mutant)IBA 03/2013 - 02/2012
2	Immune Checkpoint InhibitorsIBA 02/2024 - 01/2022
2	Histone Deacetylase InhibitorsIBA 05/2023 - 05/2014
2	gonadotropin releasing hormone associated peptideIBA 01/2023 - 05/2021
2	tyrosine receptor (receptor, tyrosine)IBA 01/2023 - 01/2014
2	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 12/2022 - 12/2013
2	EnzymesIBA 09/2022 - 01/2017
2	Reticulin (Reticular Fiber)IBA 01/2022 - 04/2014
2	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 01/2021 - 02/2016
2	Adrenocorticotropic Hormone (ACTH)FDA Link 01/2020 - 02/2006
2	NucleotidesIBA 01/2020 - 01/2016
2	ChromatinIBA 01/2019 - 03/2016
2	Bevacizumab (Avastin)FDA Link 01/2018 - 01/2016
2	MethyltransferasesIBA 01/2018 - 01/2018
2	isocitric acid (isocitrate)IBA 01/2018 - 08/2010
2	Lactic Acid (Lactate)FDA LinkGeneric 09/2017 - 07/2005
2	Glial Fibrillary Acidic ProteinIBA 05/2017 - 10/2014
2	Lomustine (CCNU)FDA Link 05/2017 - 01/2016
2	Alkylating AgentsIBA 02/2016 - 02/2008
2	Carmustine (FIVB)FDA Link 02/2016 - 11/2013
2	ProlactinIBA 01/2016 - 02/2006
2	Neurofibromin 1 (Neurofibromin)IBA 01/2016 - 04/2014
2	EpitopesIBA 10/2015 - 02/2015
2	AntibodiesIBA 10/2013 - 07/2005
2	O(6)-Methylguanine-DNA MethyltransferaseIBA 08/2013 - 02/2008
2	Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA 03/2012 - 07/2011
2	Angiogenesis InhibitorsIBA 02/2012 - 09/2010
1	Brain-Derived Neurotrophic Factor (BDNF)IBA 05/2024
1	B7-H1 AntigenIBA 02/2024
1	tovorafenibIBA 01/2024

Therapy/Procedure

39	Therapeutics 01/2024 - 04/2009
11	Drug Therapy (Chemotherapy) 01/2024 - 02/2008
10	Radiotherapy 12/2023 - 02/2012
4	Chemoradiotherapy 01/2021 - 10/2014
4	Ligation 01/2018 - 05/2013
3	Immunotherapy 10/2023 - 02/2015
3	Operative Surgical Procedures 10/2023 - 05/2021
2	Heterologous Transplantation (Xenotransplantation) 05/2024 - 08/2023
2	Aftercare (After-Treatment) 12/2017 - 01/2016
1	Adjuvant Radiotherapy 05/2024